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An emerging biomarker for Acute Kidney Injury

The Triage^® NGAL Test is a point-of-care fluorescence immunoassay to be used with the Triage^® Meters for the rapid, quantitative determination of Neutrophil Gelatinase Associated Lipocalin (NGAL) in EDTA anticoagulated whole blood or plasma specimens.

• Quantitative results in 15 minutes
• Available under CE Mark approval
  

Under normal conditions. NGAL is detected at very low levels in several human tissues, including the kidneys. However, the expression of NGAL becomes markedly induced in the post-ischemic kidney and it has been suggested that NGAL may play a role in repair and nephrogenesis.^1-4

Several studies have illustrated a link between elevated NGAL levels and the incidence of Acute Kidney Injury (AKI) One such study recently reported NGAL elevations in association with AKI in patients presenting to the Emergency Department.⁵  Other studies have demonstrated an increase in NGAL in the setting of Contrast Induced Nephropathy (CIN), AKI post Cardio-Pulmonary Bypass surgery as well as AKI in the general lCU population.

For a copy of the brochure and for full references click here

For your copy of Biomarkers in Acute Kidney Injury (AKI) Conference Report click on the 'Related Articles' section below

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