Customer Care Tel: 0161 483 5884
Email: ukcustomer@alere.com
Website: www.alere.co.uk
Connecting withFlow Cytometry
Limited FREE SAMPLES on Dako Kappa and Lambda Antibodies
Alere are very pleased to be able to supply the Dako Kappa and Lambda antibodies. These antibodies are available in a range of fluorochromes and combinations as detailed below.
The kappa and lambda antibodies are of exceedingly high quality and are a very popular choice. This is exemplified by the customer testimonials below. We are currently running a promotion on this range to offer new users the chance to evaluate the Dako clones and see first hand how well these antibodies perform.
If you would like to take up this offer please click on the enquiry button below and we will contact you. We look forward to hearing from you and providing the antibodies you need.
For your reference we have created an area on the website where you can leave your feedback and ideas. Should you wish to leave any suggestions as to what you would like to see become available please leave your feedback here
“'The detection of light chain restriction within B lymphoid populations can be a powerful tool to demonstrate clonality. We have used the Dako Kappa-FITC and Dako Lambda -PE in combination with a B cell antigen (Dako CD19 or Dako CD20) for many years in the diagnosis of B cell lymphoproliferative disorders. In our hands, they are the reagents of choice.'”
David Bloxham | Haematology, Addenbrookes Hospital
“'We have used the triple multimix CD19 FITC/Lambda RPE/Kappa APC for the last year and have found it excellent for enumeration of Kappa and Lambda expressing B cells. This is particularly so in the investigation of some lymphoproliferative disorders such as CLL where the expression of Kappa or Lambda may be very weak. The choice of fluorochromes for the Kappa and Lambda is ideal as it utilises bright fluorochromes and hence provides better staining than some other commercial reagents. We have also found the premixed combination convenient to use in our laboratory.'”
Charlie Pearson | Haematology, Glasgow Royal Infirmary
“'Immunophenotyping by flow cytometry is an essential requisite for the diagnosis of mature B-cell lymphoid malignancy. The latter can be distinguished from normal B-cells by the identification of the main two types of phenotypic abnormalitiies: Ig light chain restriction and aberrant antigen expression. In contrast to most normal and reactive populations, neoplasma of mature B-cells usually represent a single clone of cells that express only one class of Ig light chain restriction. i.e. kappa or lambda. The Dako reagent that combines polyclonal kappa FITC and lambda PE conjugates is designed to detect light chain expression in normal and neoplastic B-cells. Using these reagents by flow cytometry one can clearly evaluate the kappa:lambda ratio.'”
Ricardo Morilla | Haemato-Oncology Section, Institute of Cancer Research