A second generation rapid ELISA for the detection of Clostridium difficile toxins A and B in fecal specimens.

After treatment with antibiotics, many patients develop gastrointestinal problems ranging from mild diarrhea to severe pseudomembranous colitis. Many cases of the milder forms of gastrointestinal illness and most cases of pseudomembranous colitis are caused by Clostridium difficile. This organism is an opportunistic anaerobic bacterium that grows in the intestine once the normal flora has been altered by antibiotics. Clostridium difficile produces two toxins, A and B. Toxin A often is referred to as the enterotoxin and toxin B is referred to as the cytotoxin. Both toxins are detected by the C. DIFFICILE TOX A/B II™. The C. DIFFICILE TOX A/B II is an ELISA and is an alternative to tissue culture assay for detecting C. difficile toxin in fecal specimens. The test is completed within one hour. Alternatively, a rapid format may be used for results within 30 minutes.

Features

Detects both toxin A and toxin B
No indeterminates
Results in an hour or less
Easy to perform
Utilizes highly specific antibodies
High correlation with tissue culture but much faster

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C. difficile Tox A/B II™

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C. difficile Tox A/B II^™